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The project is currently in an under-construction stage with the possession scheduled to be in possession on Dec Sector 7 is bordered by important roads that render smooth connectivity to other major places of the city. There are also hospitals, schools, malls, banks and parks in the area. Property ID : None. Area Sq Ft. Rurban Santushti Estate Overview:. Screenshot from Ventura County Planning Division report on the project Flare the Ventura County Board of Supervisors will consider allowing to flare gas full time for the next 25 years on Koenigstein Road.

County supervisors continued to Tuesday, June 22 at 4 p. Read more: Supervisors to vote June 22 on proposal for full-time gas flare for 25 years in Upper Ojai. How to resolve AdBlock issue?

Refresh this page. News Hello, Ojai Living Treasures! Because July 4 is on Sunday this year, organizers will hold the Independence Day parade and fireworks show on Saturday, July 3. James Fryhoff. The City Council adopted an emergency ordinance for formula businesses in a vote on June 22 with Councilmember Ryan Blatz dissenting.

A man arrested on suspicion of arson for a small brush fire near Meiners Oaks June 18 has been released from jail pending further investigation in the case, authorities said. Using a traditional approach of landscape ecology, this study evaluates the spatial structure of a simulated landscape based on different levels of vulnerability to land degradation using 15 metrics calculated at three time points earlys, earlys, earlys in Italy.

While the average level of land vulnerability increased over time almost in all Italian regions, vulnerable landscapes demonstrated to be increasingly fragmented, as far as the number of homogeneous patches and mean patch size are concerned. The spatial balance in affected and unaffected areas-typically observed in the s-was progressively replaced with an intrinsically disordered landscape, and this process was more intense in regions exposed to higher and increasing levels of land degradation.

The spread of larger land patches exposed to intrinsic degradation brings to important consequences since 1 the rising number of hotspots may increase the probability of local-scale degradation processes, and 2 the buffering effect of neighbouring unaffected land can be less effective on bigger hotspots, promoting a downward spiral toward desertification. Target enrichment long-read sequencing with adaptive sampling can determine the structure of the small supernumerary marker chromosomes Structural analysis of small supernumerary marker chromosomes sSMCs has revealed that many have complex structures.

Structural analysis of sSMCs by whole genome sequencing using short-read sequencers is challenging however because most present with a low level of mosaicism and consist of a small region of the involved chromosome. In this present study, we applied adaptive sampling using nanopore long-read sequencing technology to enrich the target region and thereby attempted to determine the structure of two sSMCs with complex structural rearrangements previously revealed by cytogenetic microarray.

In adaptive sampling, simple specification of the target region in the FASTA file enables to identify whether or not the sequencing DNA is included in the target, thus promoting efficient long-read sequencing. To evaluate the target enrichment efficiency, we performed conventional pair-end short-read sequencing in parallel. Sequencing with adaptive sampling achieved a target enrichment at about a This enabled us to quickly identify all breakpoint junctions and determine the exact sSMC structure as a ring chromosome.

In addition to the microhomology and microinsertion at the junctions, we identified inverted repeat structure in both sSMCs, suggesting the common generation mechanism involving replication impairment. Adaptive sampling is thus an easy and beneficial method of determining the structures of complex chromosomal rearrangements.

The dynamical formation of ephemeral groups on networks and their effects on epidemics spreading In network models of propagation processes, the individual, microscopic level perspective is the norm, with aggregations studied as possible outcomes. On the contrary, we adopted a mesoscale perspective with groups as the core element and in this sense we present a novel agent-group dynamic model of propagation in networks. In particular, we focus on ephemeral groups that dynamically form, create new links, and dissolve.

The experiments simulated model configurations and produced results describing cases of consecutive and non-consecutive dynamic grouping, bounded or unbounded in the number of repetitions. Results revealed the existence of complex dynamics and multiple behaviors. An efficiency metric is introduced to compare the different cases. A Null Model analysis disclosed a pattern in the difference between the group and random models, varying with the size of groups.

Our findings indicate that a mesoscopic construct like the ephemeral group, based on assumptions about social behavior and absent any microscopic level change, could produce and describe complex propagation dynamics. A conclusion is that agent-group dynamic models may represent a powerful approach for modelers and a promising new direction for future research in models of coevolution between propagation and behavior in society.

Transiently hypoxic tumour cell turnover and radiation sensitivity in human tumour xenografts Solid tumour perfusion can be unstable, creating transiently hypoxic cells that can contribute to radiation resistance. We investigated the in vivo lifetime of transiently hypoxic tumour cells and chronically hypoxic tumour cells during tumour growth and following irradiation.

Hypoxic cells in SiHa and WiDr human tumour xenografts were labelled Postmortem high-dimensional immune profiling of severe COVID patients reveals distinct patterns of immunosuppression and immunoactivation A complete diagnostic autopsy is the gold-standard to gain insight into Coronavirus disease COVID pathogenesis.

Finally, viral load positively correlates with specific immunosuppression and dendritic cell markers. Estimating null and potent modes of feedforward communication in a computational model of cortical activity Communication across anatomical areas of the brain is key to both sensory and motor processes. Dimensionality reduction approaches have shown that the covariation of activity across cortical areas follows well-delimited patterns.

Some of these patterns fall within the "potent space" of neural interactions and generate downstream responses; other patterns fall within the "null space" and prevent the feedforward propagation of synaptic inputs.

Despite growing evidence for the role of null space activity in visual processing as well as preparatory motor control, a mechanistic understanding of its neural origins is lacking.

Here, we developed a mean-rate model that allowed for the systematic control of feedforward propagation by potent and null modes of interaction. In this model, altering the number of null modes led to no systematic changes in firing rates, pairwise correlations, or mean synaptic strengths across areas, making it difficult to characterize feedforward communication with common measures of functional connectivity.